Writing in the Guardian, Ben Goldacre reveals the shocking truth about the drugs that doctors prescribe: thanks to aggressive manipulation from the pharmaceutical companies and passivity from regulators, doctors often don’t know that the drugs were ineffective (or harmful) in a majority of their clinical trials. That’s because pharma companies set up their trials so that they [have?] the right to terminate ones that look unpromising (or stop them early if they look promising and report on the result partway through as though it reflected the whole trial), and to simply suppress the results of negative trials.
As a result, doctors – even doctors who do their homework and pay close attention to the published trials, examining their methodology carefully – end up prescribing useless (or harmful) medicines. And according to Goldacre, this is true of all doctors in every country, because every country’s regulators allow pharmaceutical companies to cynically manipulate research outcomes to increase their profits.
There's more, lots more, in Cory’s original post – and Cory Doctorow is not the sort of person who uses the word “shocking” lightly. He is also well aware of the problems which might ensue if he has been writing untruths. I have seen nothing to indicate that this is happening!
Just read it. There's so much more. Paroxetine, a drug that was known to be ineffective for treating children, which had a risk of suicide as a side-effect, widely prescribed to children, because GlaxoSmithKline declined to publish its research data after an internal memo stated "It would be commercially unacceptable to include a statement that efficacy had not been demonstrated, as this would undermine the profile of paroxetine."The drugs don't work: a modern medical scandal